Stress reduction programs in patients with elevated blood. Available data from pubmed, web of science, china national knowledge. How does exercise treatment compare with antihypertensive. Effects of hypertension, diabetes and coronary heart disease.
Blood and urine cadmium, blood pressure, and hypertension. The association between hypertension and dvt after orthopedic surgery was. Its major purposes are to increase the numbers of observations and the statistical power, and to improve the estimates of the effect size of an intervention or an association. Besides many publications on the association of red cell distribution width rdw and preeclampsia, there has been no published metaanalysis. The recent publication of a new metaanalysis of 14 randomized trials of antihypertensive drug therapy in the lancet has heightened the debate regarding the. Research paper does comorbidity increase the risk of patients. For the primary analysis using only prospective studies, we conducted 30 metaanalyses of hypertension and 16 different cancers, and 29 metaanalyses between sbp or dbp and 11 cancers. The meta analysis table lists the prevalence of hypertension expressed as a percentage, with their 95%ci found in the individual studies included in the meta analysis. Metaanalysis allows you to determine the overall effect on the basis of the studies effects. Effects of hypertension, diabetes and coronary heart. Risk of hypertension in cancer patients treated with abiraterone. Metaanalysis of hypertension trials in diabetic patients marco pahor, bruce m. The dashed line indicates the pooled restricted cubic spline model, and the solid lines indicate the 95% cis of the pooled curve. Jun 16, 2008 our meta analysis suggests that garlic preparations are superior to placebo in reducing blood pressure in individuals with hypertension.
We identified 123 studies with 6 815 participants for the tabular metaanalysis. Renal denervation and blood pressure reduction in resistant hypertension. The results of metaanalysis will be relatively accurate. However, a large proportion of the population with hypertension remains undiagnosed, untreated, or inadequately treated, contributing to the rising burden of cardiovascular disease in the region. Therefore, our meta analysis including western and korean studies may underestimate the effect of acupuncture for hypertension.
This meta analysis is to analyze the correlation between hypertension, diabetes, coronary heart disease and covid19 disease severity. The burden and high prevalence of hypertension in pakistani adolescents. The interpretation and reporting of these data are the responsibility of the authors and in no way should be seen as an official policy of or interpretation by the national institutes of health nih. The inverse variance method with a randomeffects model was used to pool the risk estimates from the individual studies.
Overall analysis of hypertension and breast cancer risk. Hypertension htn and smoking are established risk factors for cardiovascular disease u. Metaanalysis renal denervation and blood pressure reduction. Table 2 shows the subgroup analyses of summary wmds in sbp and dbp. Covid19 patients with chronic diseases such as hypertension, diabetes and coronary heart diseases is more likely to worsen, but with mixed results for covid19 severity. Comparators in eligible medication trials included placebo, other medications, doses, or usual care. The pooled proportion prevalence with 95%ci is given for the random effects model. Association between blood pressure and risk of cancer.
Globally, hypertension is the leading cause of cardiovascular disease and cardiovascular mortality, with more than 1 billion adults affected worldwide and 10. Blood pressure lowering for prevention of cardiovascular disease. We then used these data to perform ipd meta analysis to evaluate the effect of selfmonitoring on bp levels and in the control of hypertension using 1 year of followup as our primary end point. Data sources we searched pubmed, cochrane library databases, embase and the science citation index expanded through december 2015. Hypertension characteristics and quality of studies six studies, including 324 severe group cases and 1234 a total of 1558 samples from 6 retrospective studies were enrolled in this metaanalysis 1, 48. Metaanalysis of the effect and safety of berberine in the. Many epidemiologic studies indicated that hypertension might play an important role in the development of cataract, while others not. Department of preventive medicine, stony brook university medical center, stony brook, new york, usa. Meta analysis of hypertension trials in diabetic patients marco pahor, bruce m. The specific contribution of abiraterone to hypertension has not been defined.
Methods the study was embedded in the kailuan study, a populationbased cohort of adults that contains underground miners. The q test and i2 statistic were used to examine betweenstudy heterogeneity. Objectives the study sought to determine the link between vitamin d concentrations and incident hypertension in prospective study and metaanalysis. Preeclampsia is a serious pregnancyrelated disease which may lead to adverse health effects to the mother and fetus. Methods study design and search strategydata source a systematic metaanalysis was done using published and unpublished articles on prevalence of hypertension in ethiopia.
The etiology of essential htn, however, is unknown carretero and oparil 2000, but cadmium exposure has been inconsistently associated with blood pressure bp. In subgroup analysis, bevacizumab dose, sample size and hypertension grade of controls may account for the presence of significant heterogeneity based on significant differences in stratified relative risk table 2. Cohen reports grants from the nih, national heart, lung, and blood institute, during the conduct of. Setting, participants and measures studies providing information on the association between frailty and hypertension in adult persons, regardless of the study setting, study design or definition of. A second sensitivity analysis was performed by comparing the metaanalysis from all 17 studies with a metaanalysis of the studies which focused on cardiac related health issues but did not have hypertension as an explicit inclusion criteria, although the majority of the participants had hypertension 19, 20, 2426.
Association between periodontitis and arterial hypertension. Metaanalysis of implementation strategies for blood pressure control. Association between hypertension and deep vein thrombosis. Mar 20, 2017 overall analysis of hypertension and breast cancer risk. Objectives the study sought to determine the link between vitamin d concentrations and incident hypertension in prospective study and meta analysis. We therefore conducted this metaanalysis to determine the relationship between risk of cataract and hypertension. Methods there is, as yet, no unanimously accepted strategy for performing a meta analysis but researchers agree that each meta analysis should beconducted like a scientific experiment and begin with a protocol, which clearly states its aim and methodology. The prevalence of hypertension is markedly higher in the urban population compared to the rural population, but the prevalence in the rural population is also a matter of concern with almost.
An overview of the metaanalyses of the hypertension. Methods we conducted a search in pubmed, embase, web of science and global index medicus to identify articles published from inception to 30. Metaanalysis now offers the opportunity to critically evaluate and statistically combine results of comparable studies or trials. Metaregression analyses showed relative risk reductions. Therefore, our metaanalysis including western and korean studies may underestimate the effect of acupuncture for hypertension.
Hypertension has been recognized as a global health concern for developing countries and is scarcely described in many of these countries. Risk of bias, publication bias, and overall certainty of evidence the studies overall had moderate to good methodological quality table 2. The results persisted in most subgroup and sensitivity analyses. The recent publication of a new metaanalysis of 14 randomized trials of antihypertensive drug therapy in the lancet has heightened the debate regarding the benefits of treatment of hypertension. Background covid19 patients with chronic diseases such as hypertension, diabetes and coronary heart diseases is more likely to worsen, but with mixed results for covid19 severity. Blood pressure, hypertension and the risk of sudden cardiac death. Relevant studies were identified by a search of pubmed, embase, china national knowledge infrastructure, wanfang, the chinese biomedical literature, and weipu database until december 2015. Six studies 1, 48 reported that hypertension, diabetes, and copd, five. The burden and high prevalence of hypertension in pakistani. The clinical outcomes and effectiveness of mhealth. For example, when analysis was restricted to studies. Doctoral program in population health and clinical outcomes research, and.
Cumulative meta analysis displaying temporal trends in idiopathic pulmonary arterial hypertension pah patients. We searched the pubmed, cochrane, embase, and proquest databases using a combination of mesh and free text, from the inception of these databases to 20 january 2020, with no language restrictions. Meta analysis of effect of vitamin d supplementation on diastolic blood pressure, update meta analysis of randomized controlled trials of the effect of vitamin d on blood pressure in the general population. Available data from pubmed, web of science, china national knowledge infrastructure database, wanfang database and vip database, were analyzed using a fixed effects model metaanalysis to derive overall odds ratios or with 95% cis. While the present metaanalysis should not be considered conclusive, it seems beneficial to prefer an ace inhibitor as a firstline agent when treating hypertension in diabetic patients. Cardiovascular risk cvd are the leading cause of mortality worldwide, accounting for 30% of all global deaths1. Increased risk of highgrade hypertension with bevacizumab. Hypertension is the primary and most common risk factor for heart disease, stroke, and renal disease and has been identified as the leading cause of mortality and third cause of disabilityadjusted life years worldwide. Effects of probiotics on patients with hypertension.
We then used these data to perform ipd metaanalysis to evaluate the effect of selfmonitoring on bp levels and in the control of hypertension using 1 year of followup as our primary end point. Data about anticoagulation in pulmonary arterial hypertension pah patients are inconsistent. Franco, c emanuele di angelantonio, a and dorairaj prabhakaran d. Eva munoz aguilera, jean suvan, jacopo buti, marta czesnikiewiczguzik, aline barbosa ribeiro, marco orlandi, tomasz j guzik, aroon d hingorani, jose nart, francesco daiuto, periodontitis is associated with hypertension. The results of meta analysis will be relatively accurate. Research paper does comorbidity increase the risk of. In 2012, we studied 2,456 men and women free of prevalent hypertension, age 21 to 67 at baseline.
Haemodynamic elevated blood pressure bp and metabolic hyperlipidaemia and. Metaanalysis of hypertension trials in diabetic patients. Dec 28, 2018 a meta analysis was performed if at least three studies used the same definition of frailty and a dichotomous definition of hypertension. As for the results of study, it is a positive conclusion, our metaanalysis shows that berberine has a therapeutic effect on type 2 dm, hyperlipidemia and hypertension and has less sideeffects. A metaanalysis was performed if at least three studies used the same definition of frailty and a dichotomous definition of hypertension. Our results provide strong support for lowering blood pressure to systolic blood pressures less than mm hg and providing blood pressure lowering treatment to individuals with a history of cardiovascular disease, coronary heart disease, stroke, diabetes, heart failure. As for the results of study, it is a positive conclusion, our meta analysis shows that berberine has a therapeutic effect on type 2 dm, hyperlipidemia and hypertension and has less sideeffects.
The highly neglected burden of resistant hypertension in. Advantages and disadvantages of the metaanalysis approach. The prevalence of hypertension among children varied significantly when measured by different devices. A metaanalysis article pdf available in plos one 912. Available data from pubmed, web of science, china national. Blood pressure lowering significantly reduces vascular risk across various baseline blood pressure levels and comorbidities. Risk of hypertension in cancer patients treated with. Six studies 1, 48 reported that hypertension, diabetes, and. Pubmed and embase databases were searched to identify all related prospective cohort studies. Methods available data from pubmed, web of science, china national knowledge infrastructure.
Department of health and human services 2000, the leading cause of death worldwide world health organization 2009. This metaanalysis is to analyze the correlation between hypertension, diabetes, coronary heart disease and covid19 disease severity. Regional differences in risk and protective factors for hypertension and differences in acupuncture techniques could substantially affect the potential efficacy of acupuncture. The objective of this study was to examine the impact of adjunctive oral anticoagulants in patients with pah through metaanalysis, and to further assess whether response differs by pah subtype. A metaanalysis of prospective cohort studies was performed to investigate the effect of pa on hypertension risk. Methods we conducted a search in pubmed, embase, web of science and global index medicus to identify articles published from inception to 30 september 2017. Pdf blood pressure lowering for prevention of cardiovascular. Bevacizumab significantly increased the risk of hypertension in cancer patients, as shown by our metaanalysis based on seven randomizedcontrolled clinical trials rcts. Is anticoagulation beneficial in pulmonary arterial hypertension. Cataract is the major cause of blindness across the world. We aimed to analyze the association between hypertension and deep vein thrombosis dvt after orthopedic surgery. Nonpharmacological treatment options for hypertension have the potential to reduce the risk of cardiovascular disease at a population level.
An overview of the metaanalyses of the hypertension treatment. Metaregression analyses showed relative risk reductions proportional to the magnitude of the blood pressure reductions achieved. We predefined levels of intensity of cointervention and subgroups of patients for further analysis. Only randomised controlled trials rcts were included. Jun 12, 2019 for the primary analysis using only prospective studies, we conducted 30 meta analyses of hypertension and 16 different cancers, and 29 meta analyses between sbp or dbp and 11 cancers. We searched the pubmed, cochrane, embase, and proquest databases using a combination of mesh and free text, from the inception of these databases to 20 january 2020, with no.
Blood pressure lowering for prevention of cardiovascular. In this metaanalysis, we aim to assess the comparative effectiveness of various implementation strategies on bp reduction in patients with. Hypertension is one of the major side effects associated with abiraterone in the treatment of advanced prostate cancer. The burden of hypertension in subsaharan africa has been increasing over the past few decades. Metaanalysis is used to evaluate the effect that is described by a number of publications. However, each meta analysis has the limitations of methodology or research object. Increased risk of highgrade hypertension with bevacizumab in. However, each metaanalysis has the limitations of methodology or research object.
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